The effectiveness of services responsible for domain security in the region is determined not only by the availability of the required forces and resources, but also by their location relative to the sources of threat and the protected entities. For this reason, the forces and resources that guarantee security in the region should be distributed in a manner that accounts for the current location of the protected entities and sources of threat to the operational security of those entities. Every entity faces various types of threats. Systems that minimize the impact of each threat should be developed to deliver a stable level of operational security in the entity. The security of an entity should be analyzed in view of various domains. This paper analyzes the concept of computer-aided determination of the optimal distribution of forces and resources that guarantee the operational security of entities in various domains. A method supporting the determination of optimal domain location was developed with the use of an expert application based on the AITECH Sphinx framework expert system. The optimal distribution of active elements protecting two entities against two types of threats was tested with the involvement of the developed application.